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Nandrolone Decanoate Interactions and Side Effects: Read Before Use

by Melissa Bell
5 minutes read

Many people looking for an off-season steroid to help them bulk up for the summer consider Nandrolone. This steroid is growing more and more popular due to the some astonishing effects claimed by some individuals. While Nandrolone is a naturally occurring steroid that appears in conversion of testosterone, it is not normally found in our bloodstream. So, what exactly is Nandrolone and what do you need to know about it before considering its use?

What Is Nandrolone And When Was It First Produced?

As you probably know, Nandrolone is a hormone that is naturally found in the conversion of testosterone. However, the steroid can be attached to a variety of different esters. Some of these esters include Decanoate, Phenylpropionate, and Cypionate. Among these different formulations the most well-known is the Nandrolone Decanoate also known as Deca Durabolin. This formula first saw light in 1960 and was later released to the public in 1962.

The Benefits Of Nandrolone Decanoate

Athletes and bodybuilders have been utilizing this steroid for a number of years now for its diverse effects. When taken in proper amount it has the power to increase strength, burn body fat and promote significant lean muscle gains. It can also help with protein synthesis, increase recovery times, improve joint health, and enhance muscle endurance. Along with this, some claim that this steroid has the power to improve appetite, lower liver toxicity, and enhance IGF-1 levels.

Nandrolone is suitable for men, woman, novice weightlifters and experienced professionals. Before getting on the train, it should be noted that some side effects can be associated with the use of this steroid.

The Side Effects Of Nandrolone

A recent study reports that Nandrolone could potentially induce psychological side effects like aggression, depression, psychosis and mood swings. However, this study was conducted on a group of adolescent rats, so it is unclear if it could potentially have the same effect on humans. The adolescent rats were given daily injections for a total of fourteen days. The rats eventually began displaying signs of aggression and depression. Some other severe side effects like bladder contractions, breast tenderness, enlarged breasts, and painful erection have also been reported in some individuals. If you experience these side effects, you should immediately stop taking it and get in touch with a physician.

Acne is another reported side effect, but this is a much less severe concern. Some Individuals have even reported chills and diarrhea, which are also less severe.

Further, Nandrolone abuse can decrease anxiety and impair memory in rats via central androgenic receptors.

A study in 2014 clearly showed that supraphysiological doses of Nandrolone Decanoate administered chronically are able to disrupt redox metabolism in the studied tissues, characterizing an oxidative stress state. This study was, again, conducted on rats.

Some rarer side effects have occasionally been noted:

  • Fluid retention in the tissues;
  • An increase in male characteristics in women; your voice may get deeper and you may notice some hair growth or acne;
  • Increased sexual desire;
  • Nausea;
  • Itching;
  • Increased hemoglobin;
  • Changes in blood lipids;
  • Abnormal liver function;
  • Liver anatomy changes;
  • Hoarseness;
  • Change of the voice;
  • Increased body or facial hair;
  • Enlargement of the clitoris;
  • Masculinization;
  • Abnormal blood tests.

All the studies we reviewed note the need for further human-based research.

Proper Dosing

When it comes to steroids, one must always use the proper dose and never overdo it. Experts recommend that woman take a dose of fifty milligrams a week for four to six weeks. Higher dosages for longer periods of time could lead to negative consequences. The recommended dosage for men is 300 to 400 milligrams per week for eight to twelve weeks. For the cutting cycle of your regime, you should stick with 200 to 300 milligrams a week. It is highly advised to never exceed more than 600 milligrams, as this could lead to unwanted side effects.

Taking Deca Safely

When it comes down to it, there are some risks associated with Deca and you need to be very cautious when using this substance. If you do not, there is a good chance that you’re going to run into trouble along the way. The good news is that taking the substance safely isn’t that difficult. First and foremost, you need to make sure that you consume Deca alongside testosterone. After all, this substance is going to cause your body to produce less testosterone.

Even after you’ve stopped taking Deca, you may still need to use testosterone. Also, make sure that you stick with the recommended doses mentioned above. This will ensure that you’re able to get the results that you need without so many risks.

Potential Gains

Most of the people using Deca are bodybuilders. This is the case, because this specific substance is capable of providing the user with significant gains. In fact, Deca tends to be more effective for developing muscle mass and bulking up than conventional steroids. If this is your primary goal, you might want to speak with your doctor and ask if Deca is right for you. It can help you achieve your workout goals quicker than you would otherwise.

If you are not a bodybuilder and just want a bit more muscles, less fat, more energy and better sleep, a HGH supplement might be a viable alternative.


When it comes down to it, while many people might want to use Nandrolone Decanoate, this may not be possible for all. Before considering Deca, make sure that this substance is legal in your area. If it is, you still might need to obtain a prescription. As always, speak to your doctor and do your research before trying any new substance to make sure it’s right for you.

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